STATE OF CALIFORNIA | |||||
ENVIRONMENTAL PROTECTION AGENCY | |||||
OFFICE OF ENVIRONMENTAL HEALTH HAZARD ASSESSMENT | |||||
SAFE DRINKING WATER AND TOXIC ENFORCEMENT ACT OF 1986 | |||||
CHEMICALS KNOWN TO THE STATE TO CAUSE CANCER OR REPRODUCTIVE TOXICITY | |||||
19/abr/13 | |||||
The Safe Drinking Water and Toxic Enforcement Act of 1986 requires that the Governor revise and republish at least once per year the list of chemicals known to the State to cause cancer or reproductive toxicity. For easy reference, chemicals which are newly added are shown in underline. Chemicals or endpoints shown in strikeout were placed on the Proposition 65 list on the date noted, and have subsequently been removed. A hyperlink is provided for the basis for removing the chemical. | |||||
In the Listing Mechanism column, "AB" denotes authoritative bodies, "SQE" denotes State's Qualified Experts, "FR" denotes formally required to be labeled or identified, and "LC" denotes Labor Code. For those chemicals for which the basis for listing documentation is available electronically, a hyperlink to the documentation is provided. The identification number indicated in the following list is the Chemical Abstracts Service (CAS) Registry Number. No CAS number is given when several substances are presented as a single listing. The date refers to the initial appearance of the chemical on the list. For those chemicals for which a no significant risk level (NSRL) for carcinogens or maximum allowable dose level (MADL) for reproductive toxicants has been adopted, it is denoted in the column, "NSRL or MADL." For those NSRLs or MADLs for which the risk assessment documentation is available electronically, a hyperlink to the documentation is provided. | |||||
Chemical | Type of Toxicity | Listing Mechanism | CAS No. | Date Listed | NSRL or MADL (µg/day)a |
A-alpha-C (2-Amino-9H-pyrido[2,3-b]indole) | cancer | AB | 26148-68-5 | 01/jan/90 | 2 |
Acetaldehyde | cancer | SQE | 75-07-0 | 01/abr/88 | 90 (inhalation) |
Acetamide | cancer | AB | 60-35-5 | 01/jan/90 | 10 |
Acetazolamide | developmental | FR | 59-66-5 | 20/ago/99 | |
Acetochlor | cancer | SQE | 34256-82-1 | 01/jan/89 | |
Acetohydroxamic acid | developmental | FR | 546-88-3 | 01/abr/90 | |
2-Acetylaminofluorene | cancer | SQE | 53-96-3 | 01/jul/87 | 0,2 |
Acifluorfen sodium | cancer | AB | 62476-59-9 | 01/jan/90 | |
Acrylamide | cancer | AB | 79-06-1 | 01/jan/90 | 0,2 |
Acrylamide | developmental, male | AB | 79-06-1 | 25/fev/11 | 140 |
Acrylonitrile | cancer | FR | 107-13-1 | 01/jul/87 | 0,7 |
Actinomycin D | cancer | FR | 50-76-0 | 01/out/89 | 0,00008 |
Actinomycin D | developmental | FR | 50-76-0 | 01/out/92 | |
AF-2;[2-(2-furyl)-3-(5-nitro-2-furyl)]acrylamide | cancer | SQE | 3688-53-7 | 01/jul/87 | 3 |
Aflatoxins | cancer | SQE | --- | 01/jan/88 | |
Alachlor | cancer | SQE | 15972-60-8 | 01/jan/89 | |
Alcoholic beverages, when associated with alcohol abuse | cancer | SQE | --- | 01/jul/88 | |
Aldrin | cancer | SQE | 309-00-2 | 01/jul/88 | 0,04 |
All-trans retinoic acid | developmental | SQE | 302-79-4 | 01/jan/89 | |
Allyl chloride Delisted October 29, 1999 [Click here for the basis for delisting] | |||||
Alprazolam | developmental | FR | 28981-97-7 | 01/jul/90 | |
Altretamine | developmental, male | FR | 645-05-6 | 20/ago/99 | |
Amantadine hydrochloride | developmental | FR | 665-66-7 | 27/fev/01 | |
Amikacin sulfate | developmental | FR | 39831-55-5 | 01/jul/90 | |
2-Aminoanthraquinone | cancer | LC | 117-79-3 | 01/out/89 | 20 |
p-Aminoazobenzene | cancer | AB | 60-09-3 | 01/jan/90 | |
o-Aminoazotoluene | cancer | SQE | 97-56-3 | 01/jul/87 | 0,2 |
4-Aminobiphenyl (4-aminodiphenyl) | cancer | LC | 92-67-1 | 27/fev/87 | 0,03 |
1-Amino-2,4-dibromoanthraquinone | cancer | AB | 81-49-2 | 26/ago/97 | |
3-Amino-9-ethylcarbazole hydrochloride | cancer | SQE | 6109-97-3 | 01/jul/89 | 9 |
2-Aminofluorene | cancer | SQE | 153-78-6 | 29/jan/99 | |
Aminoglutethimide | developmental | FR | 125-84-8 | 01/jul/90 | |
Aminoglycosides | developmental | FR | --- | 01/out/92 | |
1-Amino-2-methylanthraquinone | cancer | LC | 82-28-0 | 01/out/89 | 5 |
2-Amino-5-(5-nitro-2-furyl)-1,3,4-thiadiazole | cancer | SQE | 712-68-5 | 01/jul/87 | 0,04 |
4-Amino-2-nitrophenol | cancer | SQE | 119-34-6 | 29/jan/99 | |
Aminopterin | developmental, female | SQE | 54-62-6 | 01/jul/87 | |
Amiodarone hydrochloride | developmental, female, male | FR | 19774-82-4 | 26/ago/97 | |
Amitraz | developmental | AB | 33089-61-1 | 30/mar/99 | |
Amitrole | cancer | SQE | 61-82-5 | 01/jul/87 | 0,7 |
Amoxapine | developmental | FR | 14028-44-5 | 15/mai/98 | |
Amsacrine | cancer | LC | 51264-14-3 | 07/ago/09 | |
tert-Amyl methyl ether | developmental | LC | 994-05-8 | 18/dez/09 | |
Anabolic steroids | female, male | FR | --- | 01/abr/90 | |
Analgesic mixtures containing Phenacetin | cancer | LC | --- | 27/fev/87 | |
Androstenedione | cancer | AB | 63-05-8 | 03/mai/11 | |
Angiotensin converting enzyme (ACE) inhibitors | developmental | FR | --- | 01/out/92 | |
Aniline | cancer | AB | 62-53-3 | 01/jan/90 | 100 |
Aniline hydrochloride | cancer | AB | 142-04-1 | 15/mai/98 | |
o-Anisidine | cancer | SQE | 90-04-0 | 01/jul/87 | 5 |
o-Anisidine hydrochloride | cancer | SQE | 134-29-2 | 01/jul/87 | 7 |
Anisindione | developmental | FR | 117-37-3 | 01/out/92 | |
Anthraquinone | cancer | AB | 84-65-1 | 28/set/07 | |
Antimony oxide (Antimony trioxide) | cancer | AB | 1309-64-4 | 01/out/90 | |
Aramite | cancer | SQE | 140-57-8 | 01/jul/87 | 20 |
Areca nut | cancer | LC | --- | 03/fev/06 | |
Aristolochic acids | cancer | LC | --- | 09/jul/04 | |
Arsenic (inorganic arsenic compounds) | cancer | LC | -- | 27/fev/87 | 0.06 (inhalation) 10 (except inhalation) |
Arsenic (inorganic oxides) | developmental | SQE | --- | 01/mai/97 | |
Asbestos | cancer | LC | 1332-21-4 | 27/fev/87 | 100 fibers/day (inhalation) |
Aspirin (NOTE: It is especially important not to use aspirin during the last three months of pregnancy, unless specifically directed to do so by a physician because it may cause problems in the unborn child or complications during delivery.) | developmental, female | SQE | 50-78-2 | 01/jul/90 | |
Atenolol | developmental | FR | 29122-68-7 | 26/ago/97 | |
Auramine | cancer | SQE | 492-80-8 | 01/jul/87 | 0,8 |
Auranofin | developmental | FR | 34031-32-8 | 29/jan/99 | |
Avermectin B1 (Abamectin) | developmental | AB | 71751-41-2 | 03/dez/10 | 4,4 |
Azacitidine | cancer | AB | 320-67-2 | 01/jan/92 | |
Azaserine | cancer | SQE | 115-02-6 | 01/jul/87 | 0,06 |
Azathioprine | cancer | LC | 446-86-6 | 27/fev/87 | 0,4 |
Azathioprine | developmental | FR | 446-86-6 | 01/set/96 | |
Azobenzene | cancer | AB | 103-33-3 | 01/jan/90 | 6 |
Barbiturates | developmental | FR | --- | 01/out/92 | |
Beclomethasone dipropionate | developmental | FR | 5534-09-8 | 15/mai/98 | |
Benomyl | developmental, male | SQE | 17804-35-2 | 01/jul/91 | |
Benthiavalicarb-isopropyl | cancer | AB | 177406-68-7 | 01/jul/08 | |
Benz[a]anthracene | cancer | SQE | 56-55-3 | 01/jul/87 | 0.033 (oral) |
Benzene | cancer | LC | 71-43-2 | 27/fev/87 | 6.4 (oral) 13 (inhalation) |
Benzene | developmental, male | SQE | 71-43-2 | 26/dez/97 | 24 (oral) 49 (inhalation) |
Benzidine [and its salts] | cancer | LC | 92-87-5 | 27/fev/87 | 0,001 |
Benzidine-based dyes | cancer | FR | --- | 01/out/92 | |
Benzodiazepines | developmental | FR | --- | 01/out/92 | |
Benzo[b]fluoranthene | cancer | SQE | 205-99-2 | 01/jul/87 | 0.096 (oral) |
Benzo[j]fluoranthene | cancer | SQE | 205-82-3 | 01/jul/87 | 0.11 (oral) |
Benzo[k]fluoranthene | cancer | SQE | 207-08-9 | 01/jul/87 | |
Benzofuran | cancer | AB | 271-89-6 | 01/out/90 | 1,1 |
Benzophenone | cancer | LC | 119-61-9 | 22/jun/12 | |
Benzo[a]pyrene | cancer | SQE | 50-32-8 | 01/jul/87 | 0,06 |
Benzotrichloride | cancer | SQE | 98-07-7 | 01/jul/87 | |
Benzphetamine hydrochloride | developmental | FR | 5411-22-3 | 01/abr/90 | |
Benzyl chloride | cancer | AB | 100-44-7 | 01/jan/90 | 4 |
Benzyl violet 4B | cancer | SQE | 1694-09-3 | 01/jul/87 | 30 |
Beryllium and beryllium compounds | cancer | SQE | --- | 01/out/87 | |
Beryllium | 0,1 | ||||
Beryllium oxide | 0,1 | ||||
Beryllium sulfate | 0,0002 | ||||
Betel quid with tobacco | cancer | AB | --- | 01/jan/90 | |
Betel quid without tobacco | cancer | LC | --- | 03/fev/06 | |
2,2-Bis(bromomethyl)-1,3-propanediol | cancer | AB | 3296-90-0 | 01/mai/96 | |
Bis(2-chloroethyl)ether | cancer | SQE | 111-44-4 | 01/abr/88 | 0,3 |
N,N-Bis(2-chloroethyl)-2-naphthylamine (Chlornapazine) | cancer | LC | 494-03-1 | 27/fev/87 | |
Bischloroethyl nitrosourea (BCNU) (Carmustine) | cancer | SQE | 154-93-8 | 01/jul/87 | |
Bischloroethyl nitrosourea (BCNU) (Carmustine) | developmental | FR | 154-93-8 | 01/jul/90 | |
Bis(chloromethyl)ether | cancer | LC | 542-88-1 | 27/fev/87 | 0,02 |
Bis(2-chloro-1-methylethyl)ether, technical grade | cancer | SQE | --- | 29/out/99 | |
11/abr/13 | |||||
Bitumens, extracts of steam-refined and air refined | cancer | AB | --- | 01/jan/90 | |
Bracken fern | cancer | AB | --- | 01/jan/90 | |
Bromacil lithium salt | developmental | AB | 53404-19-6 | 18/mai/99 | |
Bromacil lithium salt | male | SQE | 53404-19-6 | 17/jan/03 | |
Bromate | cancer | AB | 15541-45-4 | 31/mai/02 | |
Bromochloroacetic acid | cancer | AB | 5589-96-8 | 06/abr/10 | |
Bromodichloromethane | cancer | AB | 75-27-4 | 01/jan/90 | 5 |
Bromoethane | cancer | AB | 74-96-4 | 22/dez/00 | 96 |
Bromoform | cancer | AB | 75-25-2 | 01/abr/91 | 64 |
1-Bromopropane (1-BP) | developmental, female, male | AB | 106-94-5 | 07/dez/04 | |
2-Bromopropane (2-BP) | female, male | AB | 75-26-3 | 31/mai/05 | |
Bromoxynil | developmental | FR | 1689-84-5 | 01/out/90 | |
Bromoxynil octanoate | developmental | AB | 1689-99-2 | 18/mai/99 | |
Butabarbital sodium | developmental | FR | 143-81-7 | 01/out/92 | |
1,3-Butadiene | cancer | SQE | 106-99-0 | 01/abr/88 | 0,4 |
1,3-Butadiene | developmental, female, male | AB | 106-99-0 | 16/abr/04 | |
1,4-Butanediol dimethanesulfonate (Busulfan) | cancer | LC | 55-98-1 | 27/fev/87 | |
1,4-Butanediol dimethanesulfonate (Busulfan) | developmental | SQE | 55-98-1 | 01/jan/89 | |
Butylated hydroxyanisole | cancer | AB | 25013-16-5 | 01/jan/90 | 4000 |
Butyl benzyl phthalate (BBP) | developmental | AB | 85-68-7 | 02/dez/05 | |
n-Butyl glycidyl ether | male | LC | 2426-08-6 | 07/ago/09 | |
beta-Butyrolactone | cancer | SQE | 3068-88-0 | 01/jul/87 | 0,7 |
Cacodylic acid | cancer | AB | 75-60-5 | 01/mai/96 | |
Cadmium | developmental, male | SQE | --- | 01/mai/97 | 4.1 (oral) |
Cadmium and cadmium compounds | cancer | SQE | --- | 01/out/87 | |
Cadmium | 0.05 (inhalation) | ||||
Caffeic acid | cancer | AB | 331-39-5 | 01/out/94 | |
Captafol | cancer | SQE | 2425-06-1 | 01/out/88 | 5 |
Captan | cancer | AB | 133-06-2 | 01/jan/90 | 300 |
Carbamazepine | developmental | FR | 298-46-4 | 29/jan/99 | |
Carbaryl | cancer | AB | 63-25-2 | 05/fev/10 | |
Carbaryl | developmental, male | LC | 63-25-2 | 07/ago/09 | |
Carbazole | cancer | AB | 86-74-8 | 01/mai/96 | 4,1 |
Carbon black (airborne, unbound particles of respirable size) | cancer | AB | 1333-86-4 | 21/fev/03 | |
Carbon disulfide | developmental, female, male | SQE | 75-15-0 | 01/jul/89 | |
Carbon monoxide | developmental | SQE | 630-08-0 | 01/jul/89 | |
Carbon tetrachloride | cancer | SQE | 56-23-5 | 01/out/87 | 5 |
Carbon-black extracts | cancer | AB | --- | 01/jan/90 | |
Carboplatin | developmental | FR | 41575-94-4 | 01/jul/90 | |
N-Carboxymethyl-N-nitrosourea | cancer | SQE | 60391-92-6 | 25/jan/02 | 0,7 |
Catechol | cancer | AB | 120-80-9 | 15/jul/03 | |
Ceramic fibers (airborne particles of respirable size) | cancer | AB | --- | 01/jul/90 | |
Certain combined chemotherapy for lymphomas | cancer | LC | --- | 27/fev/87 | |
Chenodiol | developmental | FR | 474-25-9 | 01/abr/90 | |
Chlorambucil | cancer | LC | 305-03-3 | 27/fev/87 | 0,002 |
Chlorambucil | developmental | SQE | 305-03-3 | 01/jan/89 | |
Chloramphenicol Delisted January 4, 2013 [Click here for the basis for delisting] | |||||
Chlorcyclizine hydrochloride | developmental | FR | 1620-21-9 | 01/jul/87 | |
Chlordane | cancer | SQE | 57-74-9 | 01/jul/88 | 0,5 |
Chlordecone (Kepone) | cancer | SQE | 143-50-0 | 01/jan/88 | 0,04 |
Chlordecone (Kepone) | developmental | SQE | 143-50-0 | 01/jan/89 | |
Chlordiazepoxide | developmental | FR | 58-25-3 | 01/jan/92 | |
Chlordiazepoxide hydrochloride | developmental | FR | 438-41-5 | 01/jan/92 | |
Chlordimeform | cancer | SQE | 6164-98-3 | 01/jan/89 | |
Chlorendic acid | cancer | SQE | 115-28-6 | 01/jul/89 | 8 |
Chlorinated paraffins (Average chain length, C12;approximately 60 percent chlorine by weight) | cancer | SQE | 108171-26-2 | 01/jul/89 | 8 |
p-Chloroaniline | cancer | AB | 106-47-8 | 01/out/94 | 1,5 |
p-Chloroaniline hydrochloride | cancer | AB | 20265-96-7 | 15/mai/98 | 1,9 |
Chlorodibromomethane Delisted October 29, 1999 [Click here for the basis for delisting] | |||||
Chloroethane (Ethyl chloride) | cancer | AB | 75-00-3 | 01/jul/90 | 150 |
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) (Lomustine) | cancer | SQE | 13010-47-4 | 01/jan/88 | |
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) (Lomustine) | developmental | FR | 13010-47-4 | 01/jul/90 | |
1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (Methyl-CCNU) | cancer | SQE | 13909-09-6 | 01/out/88 | |
Chloroform | cancer | SQE | 67-66-3 | 01/out/87 | 20 (oral) 40 (inhalation) |
Chloroform | developmental | LC | 67-66-3 | 07/ago/09 | |
Chloromethyl methyl ether (technical grade) | cancer | LC | 107-30-2 | 27/fev/87 | 0,3 |
3-Chloro-2-methylpropene | cancer | SQE | 563-47-3 | 01/jul/89 | 5 |
1-Chloro-4-nitrobenzene | cancer | SQE | 100-00-5 | 29/out/99 | |
4-Chloro-o-phenylenediamine | cancer | SQE | 95-83-0 | 01/jan/88 | 40 |
Chloroprene | cancer | AB | 126-99-8 | 02/jun/00 | |
2-Chloropropionic acid | male | LC | 598-78-7 | 07/ago/09 | |
Chlorothalonil | cancer | SQE | 1897-45-6 | 01/jan/89 | 41 |
p-Chloro-o-toluidine | cancer | AB | 95-69-2 | 01/jan/90 | 3 |
p-Chloro-o-toluidine, strong acid salts of | cancer | AB | --- | 15/mai/98 | |
p-Chloro-o-toluidine, hydrochloride | 3,3 | ||||
5-Chloro-o-toluidine and its strong acid salts | cancer | SQE | --- | 24/out/97 | |
Chlorotrianisene | cancer | FR | 569-57-3 | 01/set/96 | |
Chlorozotocin | cancer | AB | 54749-90-5 | 01/jan/92 | 0,003 |
Chlorsulfuron [Click here for the basis for removal of male reproductive toxicity endpoint] | developmental,
female, |
AB | 64902-72-3 | 14/mai/99 | |
Chromium (hexavalent compounds) | cancer | LC | --- | 27/fev/87 | 0.001 (inhalation) |
Chromium (hexavalent compounds) | developmental, female, male | SQE | --- | 19/dez/08 | 8.2 (oral) |
Chrysene | cancer | AB | 218-01-9 | 01/jan/90 | 0.35 (oral) |
C.I. Acid Red 114 | cancer | AB | 6459-94-5 | 01/jul/92 | |
C.I. Basic Red 9 monohydrochloride | cancer | SQE | 569-61-9 | 01/jul/89 | 3 |
C.I. Direct Blue 15 | cancer | AB | 2429-74-5 | 26/ago/97 | |
C.I. Direct Blue 218 | cancer | AB | 28407-37-6 | 26/ago/97 | 50 |
C.I. Disperse Yellow 3 | cancer | SQE | 2832-40-8 | 08/fev/13 | |
C.I. Solvent Yellow 14 | cancer | AB | 842-07-9 | 15/mai/98 | |
Ciclosporin (Cyclosporin A; Cyclosporine) | cancer | AB | 59865-13-3; 79217-60-0 | 01/jan/92 | |
Cidofovir | cancer, developmental, female, male | FR | 113852-37-2 | 29/jan/99 | |
Cinnamyl anthranilate | cancer | SQE | 87-29-6 | 01/jul/89 | 200 |
Cisplatin | cancer | SQE | 15663-27-1 | 01/out/88 | |
Citrus Red No. 2 | cancer | LC | 6358-53-8 | 01/out/89 | |
Cladribine | developmental | FR | 4291-63-8 | 01/set/96 | |
Clarithromycin | developmental | FR | 81103-11-9 | 01/mai/97 | |
Clobetasol propionate | developmental, female | FR | 25122-46-7 | 15/mai/98 | |
Clofibrate | cancer | FR | 637-07-0 | 01/set/96 | |
Clomiphene citrate | developmental | FR | 50-41-9 | 01/abr/90 | |
Clorazepate dipotassium | developmental | FR | 57109-90-7 | 01/out/92 | |
Cobalt metal powder | cancer | AB | 7440-48-4 | 01/jul/92 | |
Cobalt [II] oxide | cancer | AB | 1307-96-6 | 01/jul/92 | |
Cobalt sulfate | cancer | LC | 10124-43-3 | 20/mai/05 | |
Cobalt sulfate heptahydrate | cancer | AB | 10026-24-1 | 02/jun/00 | |
Cocaine | developmental, female | SQE | 50-36-2 | 01/jul/89 | |
Coconut oil diethanolamine condensate (cocamide diethanolamine) | cancer | LC | 68603-42-9 | 22/jun/12 | |
Codeine phosphate | developmental | FR | 52-28-8 | 15/mai/98 | |
Coke oven emissions | cancer | LC | --- | 27/fev/87 | 0,3 |
Colchicine | developmental, male | FR | 64-86-8 | 01/out/92 | |
Conjugated estrogens | cancer | LC | --- | 27/fev/87 | |
Conjugated estrogens | developmental | FR | --- | 01/abr/90 | |
Creosotes | cancer | SQE | --- | 01/out/88 | |
p-Cresidine | cancer | SQE | 120-71-8 | 01/jan/88 | 5 |
Cumene | cancer | AB | 98-82-8 | 06/abr/10 | |
Cupferron | cancer | SQE | 135-20-6 | 01/jan/88 | 3 |
Cyanazine | developmental | FR | 21725-46-2 | 01/abr/90 | |
Cycasin | cancer | SQE | 14901-08-7 | 01/jan/88 | |
Cycloate | developmental | AB | 1134-23-2 | 19/mar/99 | |
Cyclohexanol Delisted January 25, 2002 [Click here for the basis for delisting] | |||||
Cycloheximide | developmental | FR | 66-81-9 | 01/jan/89 | |
Cyclopenta[cd]pyrene | cancer | LC | 27208-37-3 | 29/abr/11 | |
Cyclophosphamide (anhydrous) | cancer | LC | 50-18-0 | 27/fev/87 | 1 |
Cyclophosphamide (anhydrous) | developmental, female, male | SQE - developmental FR - female, male | 50-18-0 | 01/jan/89 | |
Cyclophosphamide (hydrated) | cancer | LC | 6055-19-2 | 27/fev/87 | 1 |
Cyclophosphamide (hydrated) | developmental, female, male | SQE - developmental FR - female, male | 6055-19-2 | 01/jan/89 | |
Cyhexatin | developmental | FR | 13121-70-5 | 01/jan/89 | |
Cytarabine | developmental | SQE | 147-94-4 | 01/jan/89 | |
Cytembena | cancer | AB | 21739-91-3 | 15/mai/98 | |
D&C Orange No. 17 | cancer | AB | 3468-63-1 | 01/jul/90 | |
D&C Red No. 8 | cancer | AB | 2092-56-0 | 01/out/90 | |
D&C Red No. 9 | cancer | AB | 5160-02-1 | 01/jul/90 | 100 |
D&C Red No. 19 | cancer | AB | 81-88-9 | 01/jul/90 | |
Dacarbazine | cancer | SQE | 4342-03-4 | 01/jan/88 | 0,01 |
Dacarbazine | developmental | FR | 4342-03-4 | 29/jan/99 | |
Daminozide | cancer | AB | 1596-84-5 | 01/jan/90 | 40 |
Danazol | developmental | FR | 17230-88-5 | 01/abr/90 | |
Dantron (Chrysazin; 1,8-Dihydroxyanthraquinone) | cancer | AB | 117-10-2 | 01/jan/92 | 9 |
Daunomycin | cancer | SQE | 20830-81-3 | 01/jan/88 | |
Daunorubicin hydrochloride | developmental | FR | 23541-50-6 | 01/jul/90 | |
2,4-D butyric acid [Click here for the basis for the removal of developmental toxicity endpoint] | AB | 94-82-6 | 18/jun/99 | 910 | |
DDD (Dichlorodiphenyl-dichloroethane) | cancer | SQE | 72-54-8 | 01/jan/89 | 2 (DDT, DDE, DDD in combination) |
DDE (Dichlorodiphenyl-dichloroethylene) | cancer | SQE | 72-55-9 | 01/jan/89 | 2 (DDT, DDE, DDD in combination) |
DDT (Dichlorodiphenyl-trichloroethane) | cancer | SQE | 50-29-3 | 01/out/87 | 2 (DDT, DDE, DDD in combination) |
o,p'-DDT | developmental, female, male | AB | 789-02-6 | 15/mai/98 | |
p,p'-DDT | developmental, female, male | AB | 50-29-3 | 15/mai/98 | |
DDVP (Dichlorvos) | cancer | SQE | 62-73-7 | 01/jan/89 | 2 |
2,4-DP (dichloroprop) Delisted January 25, 2002 [Click here for the basis for delisting] | |||||
Demeclocycline hydrochloride (internal use) | developmental | FR | 64-73-3 | 01/jan/92 | |
N,N'-Diacetylbenzidine | cancer | LC | 613-35-4 | 01/out/89 | |
2,4-Diaminoanisole | cancer | FR | 615-05-4 | 01/out/90 | 30 |
2,4-Diaminoanisole sulfate | cancer | SQE | 39156-41-7 | 01/jan/88 | 50 |
4,4'-Diaminodiphenyl ether (4,4'-Oxydianiline) | cancer | SQE | 101-80-4 | 01/jan/88 | 5 |
2,4-Diaminotoluene | cancer | SQE | 95-80-7 | 01/jan/88 | 0,2 |
Diaminotoluene (mixed) | cancer | AB | --- | 01/jan/90 | |
Diazepam | developmental | FR | 439-14-5 | 01/jan/92 | |
Diazoaminobenzene | cancer | LC | 136-35-6 | 20/mai/05 | |
Diazoxide | developmental | FR | 364-98-7 | 27/fev/01 | |
Dibenz[a,h]acridine | cancer | SQE | 226-36-8 | 01/jan/88 | |
Dibenz[a,j]acridine | cancer | SQE | 224-42-0 | 01/jan/88 | |
Dibenz[a,h]anthracene | cancer | SQE | 53-70-3 | 01/jan/88 | 0,2 |
7H-Dibenzo[c,g]carbazole | cancer | SQE | 194-59-2 | 01/jan/88 | 0.0030 (oral) |
Dibenzo[a,e]pyrene | cancer | SQE | 192-65-4 | 01/jan/88 | |
Dibenzo[a,h]pyrene | cancer | SQE | 189-64-0 | 01/jan/88 | 0.0054 (oral) |
Dibenzo[a,i]pyrene | cancer | SQE | 189-55-9 | 01/jan/88 | 0.0050 (oral) |
Dibenzo[a,l]pyrene | cancer | SQE | 191-30-0 | 01/jan/88 | |
Dibromoacetic acid | cancer | AB | 631-64-1 | 17/jun/08 | |
Dibromoacetonitrile | cancer | AB | 3252-43-5 | 03/mai/11 | |
1,2-Dibromo-3-chloropropane (DBCP) | cancer | FR | 96-12-8 | 01/jul/87 | 0,1 |
1,2-Dibromo-3-chloropropane (DBCP) | male | LC | 96-12-8 | 27/fev/87 | 3.1 (oral) 4.3 (inhalation) |
2,3-Dibromo-1-propanol | cancer | AB | 96-13-9 | 01/out/94 | |
Dichloroacetic acid | cancer | AB | 79-43-6 | 01/mai/96 | |
Dichloroacetic acid | male | LC | 79-43-6 | 07/ago/09 | |
p-Dichlorobenzene | cancer | SQE | 106-46-7 | 01/jan/89 | 20 |
3,3'-Dichlorobenzidine | cancer | SQE | 91-94-1 | 01/out/87 | 0,6 |
3,3'-Dichlorobenzidine dihydrochloride | cancer | AB | 612-83-9 | 15/mai/98 | |
1,1-Dichloro-2,2-bis(p-chloropheny)ethylene (DDE) | developmental, male | AB | 72-55-9 | 30/mar/10 | |
1,4-Dichloro-2-butene | cancer | AB | 764-41-0 | 01/jan/90 | |
3,3'-Dichloro-4,4'-diamino-diphenyl ether | cancer | SQE | 28434-86-8 | 01/jan/88 | |
1,1-Dichloroethane | cancer | AB | 75-34-3 | 01/jan/90 | 100 |
Dichloromethane (Methylene chloride) | cancer | SQE | 75-09-2 | 01/abr/88 | 50 200 (inhalation) |
Dichlorophene | developmental | AB | 97-23-4 | 27/abr/99 | |
Dichlorphenamide | developmental | FR | 120-97-8 | 27/fev/01 | |
Diclofop-methyl | cancer | AB | 51338-27-3 | 06/abr/10 | |
Diclofop methyl | developmental | AB | 51338-27-3 | 05/mar/99 | |
1,2-Dichloropropane | cancer | AB | 78-87-5 | 01/jan/90 | 9,7 |
1,3-Dichloro-2-propanol (1,3-DCP) | cancer | SQE | 96-23-1 | 08/out/10 | |
1,3-Dichloropropene | cancer | SQE | 542-75-6 | 01/jan/89 | |
Dicumarol | developmental | FR | 66-76-2 | 01/out/92 | |
Dieldrin | cancer | SQE | 60-57-1 | 01/jul/88 | 0,04 |
Dienestrol Delisted January 4, 2013 [Click here for the basis for delisting] | |||||
Diepoxybutane | cancer | SQE | 1464-53-5 | 01/jan/88 | |
Diesel engine exhaust | cancer | AB | --- | 01/out/90 | |
Diethanolamine | cancer | LC | 111-42-2 | 22/jun/12 | |
Di(2-ethylhexyl)phthalate | cancer | SQE | 117-81-7 | 01/jan/88 | 310 |
Di(2-ethylhexyl)phthalate | developmental, male | AB | 117-81-7 | 24/out/03 | |
Adultb | 4200 (intravenous) | ||||
Infant boys, age 29 days to 24 monthsb | 600 (intravenous) | ||||
Neonatal infant boys, age 0 to 28 daysb | 210 (intravenous) | ||||
Adultb | 410 (oral) | ||||
Infant boys, age 29 days to 24 monthsb | 58 (oral) | ||||
Neonatal infant boys, age 0 to 28 daysb | 20 (oral) | ||||
1,2-Diethylhydrazine | cancer | SQE | 1615-80-1 | 01/jan/88 | |
Diethylstilbestrol (DES) | cancer | LC | 56-53-1 | 27/fev/87 | 0,002 |
Diethylstilbestrol (DES) | developmental | FR | 56-53-1 | 01/jul/87 | |
Diethyl sulfate | cancer | SQE | 64-67-5 | 01/jan/88 | |
Diflunisal | developmental, female | FR | 22494-42-4 | 29/jan/99 | |
Diglycidyl ether | male | LC | 2238-07-5 | 07/ago/09 | |
Diglycidyl resorcinol ether (DGRE) | cancer | SQE | 101-90-6 | 01/jul/89 | 0,4 |
Dihydroergotamine mesylate | developmental | FR | 6190-39-2 | 01/mai/97 | |
Dihydrosafrole | cancer | SQE | 94-58-6 | 01/jan/88 | 20 |
Diisopropyl sulfate | cancer | AB | 2973-10-6 | 01/abr/93 | |
Di-isodecyl phthalate (DIDP) | developmental | AB | 68515-49-1/ 26761-40-0 | 20/abr/07 | 2200 |
Diltiazem hydrochloride | developmental | FR | 33286-22-5 | 27/fev/01 | |
3,3'-Dimethoxybenzidine (o-Dianisidine) | cancer | SQE | 119-90-4 | 01/jan/88 | 0,15 |
3,3'-Dimethoxybenzidine dihydrochloride | cancer | AB | 20325-40-0 | 01/out/90 | 0,19 |
3,3'-Dimethoxybenzidine-based dyes metabolized to 3,3'-dimethoxybenzidine | cancer | AB | --- | 11/jun/04 | |
N,N-Dimethylacetamide | developmental | LC | 127-19-5 | 21/mai/10 | |
4-Dimethylaminoazobenzene | cancer | SQE | 60-11-7 | 01/jan/88 | 0,2 |
trans-2-[(Dimethylamino)methylimino]-5-[2-(5-nitro-2-furyl)vinyl]-1,3,4-oxadiazole | cancer | SQE | 55738-54-0 | 01/jan/88 | 2 |
7,12-Dimethylbenz(a)anthracene | cancer | AB | 57-97-6 | 01/jan/90 | 0,003 |
3,3'-Dimethylbenzidine (ortho-Tolidine) | cancer | SQE | 119-93-7 | 01/jan/88 | 0,044 |
3,3'-Dimethylbenzidine dihydrochloride | cancer | AB | 612-82-8 | 01/abr/92 | 0,059 |
3,3'-Dimethylbenzidine-based dyes metabolized to 3,3'-dimethylbenzidine | cancer | AB | --- | 11/jun/04 | |
Dimethylcarbamoyl chloride | cancer | SQE | 79-44-7 | 01/jan/88 | 0,05 |
1,1-Dimethylhydrazine (UDMH) | cancer | LC | 57-14-7 | 01/out/89 | |
1,2-Dimethylhydrazine | cancer | SQE | 540-73-8 | 01/jan/88 | 0,001 |
2,6-Dimethyl-N-nitrosomorpholine (DMNM) | cancer | SQE | 1456-28-6 | 08/fev/13 | |
Dimethyl sulfate | cancer | SQE | 77-78-1 | 01/jan/88 | |
Dimethylvinylchloride | cancer | SQE | 513-37-1 | 01/jul/89 | 20 |
Di-n-butyl phthalate (DBP) | developmental, female, male | AB | 84-74-2 | 02/dez/05 | 8,7 |
Di-n-hexyl phthalate (DnHP) | female, male | AB | 84-75-3 | 02/dez/05 | 2200 (oral) |
m-Dinitrobenzene | male | AB | 99-65-0 | 01/jul/90 | 38 |
o-Dinitrobenzene | male | AB | 528-29-0 | 01/jul/90 | |
p-Dinitrobenzene | male | AB | 100-25-4 | 01/jul/90 | |
3,7-Dinitrofluoranthene | cancer | AB | 105735-71-5 | 26/ago/97 | |
3,9-Dinitrofluoranthene | cancer | AB | 22506-53-2 | 26/ago/97 | |
1,3-Dinitropyrene | cancer | LC | 75321-20-9 | 02/nov/12 | |
1,6-Dinitropyrene | cancer | AB | 42397-64-8 | 01/out/90 | |
1,8-Dinitropyrene | cancer | AB | 42397-65-9 | 01/out/90 | |
2,4-Dinitrotoluene | cancer | SQE | 121-14-2 | 01/jul/88 | 2 |
2,4-Dinitrotoluene | male | AB | 121-14-2 | 20/ago/99 | |
2,6-Dinitrotoluene | cancer | SQE | 606-20-2 | 01/jul/95 | |
2,6-Dinitrotoluene | male | AB | 606-20-2 | 20/ago/99 | |
Dinitrotoluene (technical grade) | female, male | AB | --- | 20/ago/99 | |
Dinitrotoluene mixture, 2,4-/2,6- | cancer | AB | --- | 01/mai/96 | |
Dinocap | developmental | FR | 39300-45-3 | 01/abr/90 | |
Dinoseb | developmental, male | FR | 88-85-7 | 01/jan/89 | |
Di-n-propyl isocinchomeronate (MGK Repellent 326) | cancer | AB | 136-45-8 | 01/mai/96 | |
1,4-Dioxane | cancer | SQE | 123-91-1 | 01/jan/88 | 30 |
Diphenylhydantoin (Phenytoin) | cancer | SQE | 57-41-0 | 01/jan/88 | |
Diphenylhydantoin (Phenytoin) | developmental | SQE | 57-41-0 | 01/jul/87 | |
Diphenylhydantoin (Phenytoin), sodium salt | cancer | SQE | 630-93-3 | 01/jan/88 | |
Direct Black 38 (technical grade) | cancer | SQE | 1937-37-7 | 01/jan/88 | 0,09 |
Direct Blue 6 (technical grade) | cancer | SQE | 2602-46-2 | 01/jan/88 | 0,09 |
Direct Brown 95 (technical grade) | cancer | SQE | 16071-86-6 | 01/out/88 | 0,1 |
Disodium cyanodithioimidocarbonate | developmental | AB | 138-93-2 | 30/mar/99 | 56 (oral) 170 (oral) as 32% pesticidal formulation |
Disperse Blue 1 | cancer | AB | 2475-45-8 | 01/out/90 | 200 |
Diuron | cancer | AB | 330-54-1 | 31/mai/02 | |
Doxorubicin hydrochloride (Adriamycin) | cancer | SQE | 25316-40-9 | 01/jul/87 | |
Doxorubicin hydrochloride (Adriamycin) | developmental, male | FR | 25316-40-9 | 29/jan/99 | |
Doxycycline (internal use) | developmental | FR | 564-25-0 | 01/jul/90 | |
Doxycycline calcium (internal use) | developmental | FR | 94088-85-4 | 01/jan/92 | |
Doxycycline hyclate (internal use) | developmental | FR | 24390-14-5 | 01/out/91 | |
Doxycycline monohydrate (internal use) | developmental | FR | 17086-28-1 | 01/out/91 | |
Endrin | developmental | AB | 72-20-8 | 15/mai/98 | |
Environmental tobacco smoke (ETS) | developmental | SQE | --- | 09/jun/06 | |
Epichlorohydrin | cancer | SQE | 106-89-8 | 01/out/87 | 9 |
Epichlorohydrin | male | AB | 106-89-8 | 01/set/96 | |
Epoxiconazole | cancer | AB | 135319-73-2 | 15/abr/11 | |
Ergotamine tartrate | developmental | FR | 379-79-3 | 01/abr/90 | |
Erionite | cancer | SQE | 12510-42-8; 66733-21-9 | 01/out/88 | |
Estradiol 17B | cancer | SQE | 50-28-2 | 01/jan/88 | 0,02 |
Estragole | cancer | SQE | 140-67-0 | 29/out/99 | |
Estrogens, steroidal | cancer | LC | --- | 19/ago/05 | |
Estrogen-progestogen (combined) used as menopausal therapy | cancer | LC | --- | 04/nov/11 | |
Estrone | cancer | SQE | 53-16-7 | 01/jan/88 | |
Estropipate | cancer, developmental | FR | 7280-37-7 | 26/ago/97 | |
Ethanol in alcoholic beverages | cancer | LC | --- | 29/abr/11 | |
Ethinylestradiol | cancer | SQE | 57-63-6 | 01/jan/88 | |
Ethionamide | developmental | FR | 536-33-4 | 26/ago/97 | |
Ethoprop | cancer | AB | 13194-48-4 | 27/fev/01 | |
Ethyl acrylate | cancer | SQE | 140-88-5 | 01/jul/89 | |
Ethyl alcohol in alcoholic beverages | developmental | SQE | --- | 01/out/87 | |
Ethylbenzene | cancer | AB | 100-41-4 | 11/jun/04 | 54 (inhalation) 41 (oral) |
Ethyl-tert-butyl ether | male | LC | 637-92-3 | 18/dez/09 | |
Ethyl dipropylthiocarbamate | developmental | AB | 759-94-4 | 27/abr/99 | 700 (oral and inhalation) 6700 (dermal) |
Ethyl-4,4'-dichlorobenzilate | cancer | AB | 510-15-6 | 01/jan/90 | 7 |
Ethylene dibromide | cancer | FR | 106-93-4 | 01/jul/87 | 0.2 (oral) 3 (inhalation) |
Ethylene dibromide | developmental, male | AB | 106-93-4 | 15/mai/98 | |
Ethylene dichloride (1,2-Dichloroethane) | cancer | SQE | 107-06-2 | 01/out/87 | 10 |
Ethylene glycol monoethyl ether | developmental, male | SQE | 110-80-5 | 01/jan/89 | 750 (oral) 960 (inhalation) |
Ethylene glycol monoethyl ether acetate | developmental, male | AB | 111-15-9 | 01/jan/93 | 1100 (oral) 1400 (inhalation) |
Ethylene glycol monomethyl ether | developmental, male | SQE | 109-86-4 | 01/jan/89 | 63 (oral) |
Ethylene glycol monomethyl ether acetate | developmental, male | AB | 110-49-6 | 01/jan/93 | 98 (oral) |
Ethyleneimine | cancer | SQE | 151-56-4 | 01/jan/88 | 0,01 |
Ethylene oxide | cancer | FR | 75-21-8 | 01/jul/87 | 2 |
Ethylene oxide | female | LC | 75-21-8 | 27/fev/87 | 20 |
Ethylene oxide | developmental, male | LC | 75-21-8 | 07/ago/09 | |
Ethylene thiourea | cancer | AB | 96-45-7 | 01/jan/88 | 20 |
Ethylene thiourea | developmental | SQE | 96-45-7 | 01/jan/93 | |
2-Ethylhexanoic acid | developmental | LC | 149-57-5 | 07/ago/09 | |
Ethyl methanesulfonate | cancer | SQE | 62-50-0 | 01/jan/88 | |
Etodolac | developmental, female | FR | 41340-25-4 | 20/ago/99 | |
Etoposide | cancer | LC | 33419-42-0 | 04/nov/11 | |
Etoposide | developmental | FR | 33419-42-0 | 01/jul/90 | |
Etoposide in combination with cisplatin and bleomycin | cancer | LC | --- | 04/nov/11 | |
Etretinate | developmental | SQE | 54350-48-0 | 01/jul/87 | |
Fenoxaprop ethyl | developmental | AB | 66441-23-4 | 26/mar/99 | |
Fenoxycarb | cancer | AB | 72490-01-8 | 02/jun/00 | |
Filgrastim | developmental | FR | 121181-53-1 | 27/fev/01 | |
Fluazifop butyl | developmental | AB | 69806-50-4 | 06/nov/98 | |
Flunisolide | developmental, female | FR | 3385-03-3 | 15/mai/98 | |
Fluorouracil | developmental | SQE | 51-21-8 | 01/jan/89 | |
Fluoxymesterone | developmental | FR | 76-43-7 | 01/abr/90 | |
Flurazepam hydrochloride | developmental | FR | 1172-18-5 | 01/out/92 | |
Flurbiprofen | developmental, female | FR | 5104-49-4 | 20/ago/99 | |
Flutamide | developmental | FR | 13311-84-7 | 01/jul/90 | |
Fluticasone propionate | developmental | FR | 80474-14-2 | 15/mai/98 | |
Fluvalinate | developmental | AB | 69409-94-5 | 06/nov/98 | |
Folpet | cancer | SQE | 133-07-3 | 01/jan/89 | 200 |
Formaldehyde (gas) | cancer | SQE | 50-00-0 | 01/jan/88 | 40 |
2-(2-Formylhydrazino)-4-(5-nitro-2-furyl)thiazole | cancer | SQE | 3570-75-0 | 01/jan/88 | 0,3 |
Fumonisin B1 | cancer | AB | 116355-83-0 | 14/nov/03 | |
Furan | cancer | AB | 110-00-9 | 01/out/93 | |
Furazolidone | cancer | AB | 67-45-8 | 01/jan/90 | |
Furmecyclox | cancer | AB | 60568-05-0 | 01/jan/90 | 20 |
Fusarin C | cancer | SQE | 79748-81-5 | 01/jul/95 | |
Gallium arsenide | cancer | LC | 1303-00-0 | 01/ago/08 | |
Ganciclovir | cancer, developmental, male | FR | 82410-32-0 | 26/ago/97 | |
Ganciclovir sodium | developmental, male | FR | 107910-75-8 | 26/ago/97 | |
Gasoline engine exhaust (condensates/extracts) | cancer | AB | --- | 01/out/90 | |
Gemfibrozil | cancer | FR | 25812-30-0 | 22/dez/00 | |
Gemfibrozil | female, male | FR | 25812-30-0 | 20/ago/99 | |
Glass wool fibers (inhalable and biopersistent) | cancer | AB | --- | 01/jul/90 | |
Glu-P-1 (2-Amino-6-methyldipyrido[1,2- a:3',2'-d]imidazole) | cancer | AB | 67730-11-4 | 01/jan/90 | 0,1 |
Glu-P-2 (2-Aminodipyrido[1,2-a:3',2'-d]imidazole) | cancer | AB | 67730-10-3 | 01/jan/90 | 0,5 |
Glycidaldehyde | cancer | SQE | 765-34-4 | 01/jan/88 | |
Glycidol | cancer | AB | 556-52-5 | 01/jul/90 | 0,54 |
Goserelin acetate | developmental, female, male | FR | 65807-02-5 | 26/ago/97 | |
Griseofulvin | cancer | AB | 126-07-8 | 01/jan/90 | |
Gyromitrin (Acetaldehyde methylformylhydrazone) | cancer | SQE | 16568-02-8 | 01/jan/88 | 0,07 |
Halazepam | developmental | FR | 23092-17-3 | 01/jul/90 | |
Halobetasol propionate | developmental | FR | 66852-54-8 | 20/ago/99 | |
Haloperidol | developmental, female | FR | 52-86-8 | 29/jan/99 | |
Halothane | developmental | FR | 151-67-7 | 01/set/96 | |
HC Blue 1 | cancer | SQE | 2784-94-3 | 01/jul/89 | 10 |
Heptachlor | cancer | SQE | 76-44-8 | 01/jul/88 | 0,2 |
Heptachlor | developmental | AB | 76-44-8 | 20/ago/99 | |
Heptachlor epoxide | cancer | SQE | 1024-57-3 | 01/jul/88 | 0,08 |
Herbal remedies containing plant species of the genus Aristolochia | cancer | LC | --- | 09/jul/04 | |
Hexachlorobenzene | cancer | SQE | 118-74-1 | 01/out/87 | 0,4 |
Hexachlorobenzene | developmental | SQE | 118-74-1 | 01/jan/89 | |
Hexachlorobutadiene | cancer | AB | 87-68-3 | 03/mai/11 | |
Hexachlorocyclohexane (technical grade) | cancer | SQE | --- | 01/out/87 | 0,2 |
Hexachlorocyclohexane (alpha isomer) | 0,3 | ||||
Hexachlorocyclohexane (beta isomer) | 0,5 | ||||
Hexachlorocyclohexane (gamma isomer) | 0,6 | ||||
Hexachlorodibenzodioxin | cancer | SQE | 34465-46- 8 | 01/abr/88 | 0,0002 |
Hexachloroethane | cancer | AB | 67-72-1 | 01/jul/90 | 20 |
2,4-Hexadienal (89% trans, trans isomer; 11% cis, trans isomer) | cancer | AB | --- | 04/mar/05 | |
Hexafluoroacetone | male | LC | 684-16-2 | 01/ago/08 | |
Hexamethylphosphoramide | cancer | SQE | 680-31-9 | 01/jan/88 | |
Hexamethylphosphoramide | male | AB | 680-31-9 | 01/out/94 | |
Histrelin acetate | developmental | FR | --- | 15/mai/98 | |
Hydramethylnon | developmental, male | AB | 67485-29-4 | 05/mar/99 | 120 (oral) |
Hydrazine | cancer | SQE | 302-01-2 | 01/jan/88 | 0,04 |
Hydrazine sulfate | cancer | SQE | 10034-93-2 | 01/jan/88 | 0,2 |
Hydrazobenzene (1,2-Diphenylhydrazine) | cancer | SQE | 122-66-7 | 01/jan/88 | 0,8 |
1-Hydroxyanthraquinone | cancer | LC | 129-43-1 | 27/mai/05 | |
Hydroxyurea | developmental | FR | 127-07-1 | 01/mai/97 | |
Idarubicin hydrochloride | developmental, male | FR | 57852-57-0 | 20/ago/99 | |
Ifosfamide | developmental | FR | 3778-73-2 | 01/jul/90 | |
Iodine-131 | developmental | SQE | 10043-66-0 | 01/jan/89 | |
Imazalil | cancer | AB | 35554-44-0 | 20/mai/11 | 11 |
Indeno [1,2,3-cd]pyrene | cancer | SQE | 193-39-5 | 01/jan/88 | |
Indium phosphide | cancer | AB | 22398-80-7 | 27/fev/01 | |
IQ (2-Amino-3-methylimidazo[4,5-f] quinoline) | cancer | AB | 76180-96-6 | 01/abr/90 | 0,5 |
Iprodione | cancer | AB | 36734-19-7 | 01/mai/96 | |
Iprovalicarb | cancer | AB | 140923-17-7 & 140923-25-7 | 01/jun/07 | |
Iron dextran complex | cancer | SQE | 9004-66-4 | 01/jan/88 | |
Isobutyl nitrite | cancer | AB | 542-56-3 | 01/mai/96 | 7,4 |
Isoprene | cancer | AB | 78-79-5 | 01/mai/96 | |
Isopyrazam | cancer | AB | 881685-58-1 | 24/jul/12 | |
Isosafrole Delisted December 8, 2006 [Click here for the basis for delisting] | |||||
Isotretinoin | developmental | SQE | 4759-48-2 | 01/jul/87 | |
Isoxaflutole | cancer | AB | 141112-29-0 | 22/dez/00 | |
Kresoxim-methyl | cancer | AB | 143390-89-0 | 03/fev/12 | |
Lactofen | cancer | SQE | 77501-63-4 | 01/jan/89 | |
Lasiocarpine | cancer | SQE | 303-34-4 | 01/abr/88 | 0,09 |
Lead | developmental, female, male | LC | --- | 27/fev/87 | 0,5 |
Lead and lead compounds | cancer | AB | --- | 01/out/92 | |
Lead | 15 (oral) | ||||
Lead acetate | cancer | SQE | 301-04-2 | 01/jan/88 | 23 (oral) |
Lead phosphate | cancer | SQE | 7446-27-7 | 01/abr/88 | 58 (oral) |
Lead subacetate | cancer | LC | 1335-32-6 | 01/out/89 | 41 (oral) |
Leather dust | cancer | LC | --- | 29/abr/11 | |
Leuprolide acetate | developmental, female, male | FR | 74381-53-6 | 26/ago/97 | |
Levodopa | developmental | FR | 59-92-7 | 29/jan/99 | |
Levonorgestrel implants | female | FR | 797-63-7 | 15/mai/98 | |
Lindane and other hexachlorocyclohexane isomers | cancer | LC | --- | 01/out/89 | |
Linuron | developmental | AB | 330-55-2 | 19/mar/99 | 460 |
Lithium carbonate | developmental | FR | 554-13-2 | 01/jan/91 | |
Lithium citrate | developmental | FR | 919-16-4 | 01/jan/91 | |
Lorazepam | developmental | FR | 846-49-1 | 01/jul/90 | |
Lovastatin | developmental | FR | 75330-75-5 | 01/out/92 | |
Lynestrenol | cancer | AB | 52-76-6 | 27/fev/01 | |
Malonaldehyde, sodium salt | cancer | AB | 24382-04-5 | 29/abr/11 | |
Mancozeb | cancer | AB | 8018-01-7 | 01/jan/90 | |
Maneb | cancer | AB | 12427-38-2 | 01/jan/90 | |
Marijuana smoke | cancer | SQE | --- | 19/jun/09 | |
Me-A-alpha-C (2-Amino-3-methyl-9H-pyrido[2,3-b]indole) | cancer | AB | 68006-83-7 | 01/jan/90 | 0,6 |
Mebendazole | developmental | FR | 31431-39-7 | 20/ago/99 | |
Medroxyprogesterone acetate | cancer | AB | 71-58-9 | 01/jan/90 | |
Medroxyprogesterone acetate | developmental | FR | 71-58-9 | 01/abr/90 | |
Megestrol acetate | developmental | FR | 595-33-5 | 01/jan/91 | |
MeIQ (2-Amino-3,4-dimethylimidazo[4,5-f]quinoline) | cancer | AB | 77094-11-2 | 01/out/94 | 0,46 |
MeIQx (2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline) | cancer | AB | 77500-04-0 | 01/out/94 | 0,41 |
Melphalan | cancer | LC | 148-82-3 | 27/fev/87 | 0,005 |
Melphalan | developmental | FR | 148-82-3 | 01/jul/90 | |
Menotropins | developmental | FR | 9002-68-0 | 01/abr/90 | |
Mepanipyrim | cancer | AB | 110235-47-7 | 01/jul/08 | |
Meprobamate | developmental | FR | 57-53-4 | 01/jan/92 | |
Mercaptopurine | developmental | FR | 6112-76-1 | 01/jul/90 | |
Mercury and mercury compounds | developmental | AB | --- | 01/jul/90 | |
Merphalan | cancer | SQE | 531-76-0 | 01/abr/88 | |
Mestranol | cancer | SQE | 72-33-3 | 01/abr/88 | |
Metam potassium | cancer | AB | 137-41-7 | 31/dez/10 | |
Methacycline hydrochloride | developmental | FR | 3963-95-9 | 01/jan/91 | |
Metham sodium | cancer | AB | 137-42-8 | 06/nov/98 | |
Metham sodium | developmental | AB | 137-42-8 | 15/mai/98 | |
Methanol | developmental | AB | 67-56-1 | 16/mar/12 | 47,000 (inhalation) 23,000 (oral) |
Methazole | developmental | AB | 20354-26-1 | 01/dez/99 | |
Methimazole | developmental | FR | 60-56-0 | 01/jul/90 | |
Methotrexate | developmental | SQE | 59-05-2 | 01/jan/89 | |
Methotrexate sodium | developmental | FR | 15475-56-6 | 01/abr/90 | |
5-Methoxypsoralen with ultraviolet A therapy | cancer | SQE | 484-20-8 | 01/out/88 | |
8-Methoxypsoralen with ultraviolet A therapy | cancer | LC | 298-81-7 | 27/fev/87 | |
2-Methylaziridine (Propyleneimine) | cancer | SQE | 75-55-8 | 01/jan/88 | 0,028 |
Methylazoxymethanol | cancer | SQE | 590-96-5 | 01/abr/88 | |
Methylazoxymethanol acetate | cancer | SQE | 592-62-1 | 01/abr/88 | |
Methyl bromide, as a structural fumigant | developmental | FR | 74-83-9 | 01/jan/93 | 810 (inhalation) |
Methyl carbamate | cancer | AB | 598-55-0 | 15/mai/98 | 160 |
Methyl chloride | developmental | AB | 74-87-3 | 10/mar/00 | |
Methyl chloride | male | LC | 74-87-3 | 07/ago/09 | |
3-Methylcholanthrene | cancer | AB | 56-49-5 | 01/jan/90 | 0,03 |
5-Methylchrysene | cancer | SQE | 3697-24-3 | 01/abr/88 | 0.0084 (oral) |
4,4'-Methylene bis(2-chloroaniline) | cancer | FR | 101-14-4 | 01/jul/87 | 0,5 |
4,4'-Methylene bis(N,N-dimethyl)benzenamine | cancer | LC | 101-61-1 | 01/out/89 | 20 |
4,4'-Methylene bis(2-methylaniline) | cancer | SQE | 838-88-0 | 01/abr/88 | 0,8 |
4,4'-Methylenedianiline | cancer | SQE | 101-77-9 | 01/jan/88 | 0,4 |
4,4'-Methylenedianiline dihydrochloride | cancer | SQE | 13552-44-8 | 01/jan/88 | 0,6 |
Methyleugenol | cancer | AB | 93-15-2 | 16/nov/01 | |
Methylhydrazine and its salts | cancer | AB | --- | 01/jul/92 | |
Methylhydrazine | 0.058 (oral) 0.090 (inhalation) | ||||
Methylhydrazine sulfate | 0,18 | ||||
2-Methylimidazole | cancer | LC | 693-98-1 | 22/jun/12 | |
4-Methylimidazole | cancer | AB | 822-36-6 | 07/jan/11 | 29 |
Methyl iodide | cancer | SQE | 74-88-4 | 01/abr/88 | |
Methyl isobutyl ketone | cancer | LC | 108-10-1 | 04/nov/11 | |
Methyl isocyanate (MIC) | developmental, female | SQE | 624-83-9 | 12/nov/10 | |
Methyl isopropyl ketone | developmental | LC | 563-80-4 | 17/fev/12 | |
Methyl mercury | developmental | SQE | --- | 01/jul/87 | |
Methylmercury compounds | cancer | AB | --- | 01/mai/96 | |
Methyl methanesulfonate | cancer | SQE | 66-27-3 | 01/abr/88 | 7 |
Methyl n-butyl ketone | male | LC | 591-78-6 | 07/ago/09 | |
2-Methyl-1-nitroanthraquinone (of uncertain purity) | cancer | SQE | 129-15-7 | 01/abr/88 | 0,2 |
N-Methyl-N'-nitro-N-nitrosoguanidine | cancer | SQE | 70-25-7 | 01/abr/88 | 0,08 |
N-Methylolacrylamide | cancer | AB | 924-42-5 | 01/jul/90 | |
N-Methylpyrrolidone | developmental | AB | 872-50-4 | 15/jun/01 | 3200 (inhalation) 17000 (dermal) |
α-Methyl styrene (alpha-Methylstyrene) | cancer | LC | 98-83-9 | 02/nov/12 | |
α-Methyl styrene | female | LC | 98-83-9 | 29/jul/11 | |
Methyltestosterone | developmental | FR | 58-18-4 | 01/abr/90 | |
Methylthiouracil | cancer | LC | 56-04-2 | 01/out/89 | 2 |
Metiram | cancer | AB | 9006-42-2 | 01/jan/90 | |
Metiram | developmental | AB | 9006-42-2 | 30/mar/99 | |
Metronidazole | cancer | SQE | 443-48-1 | 01/jan/88 | |
Michler's ketone | cancer | SQE | 90-94-8 | 01/jan/88 | 0,8 |
Midazolam hydrochloride | developmental | FR | 59467-96-8 | 01/jul/90 | |
Minocycline hydrochloride (internal use) | developmental | FR | 13614-98-7 | 01/jan/92 | |
Mirex | cancer | SQE | 2385-85-5 | 01/jan/88 | 0,04 |
Misoprostol | developmental | FR | 59122-46-2 | 01/abr/90 | |
Mitomycin C | cancer | SQE | 50-07-7 | 01/abr/88 | 0,00009 |
Mitoxantrone hydrochloride | developmental | FR | 70476-82-3 | 01/jul/90 | |
Molinate | developmental, female, male | AB | 2212-67-1 | 11/dez/09 | |
MON 4660 (dichloroacetyl-1-oxa-4-azaspiro(4,5)-decane | cancer | AB | 71526-07-3 | 22/mar/11 | |
MON 13900 (furilazole) | cancer | AB | 121776-33-8 | 22/mar/11 | |
3-Monochloropropane-1,2-diol (3-MCDP) | cancer | SQE | 96-24-2 | 08/out/10 | |
Monocrotaline | cancer | SQE | 315-22-0 | 01/abr/88 | 0,07 |
MOPP (vincristine-prednisone-nitrogen mustard-procarbazine mixture) | cancer | LC | 113803-47-7 | 04/nov/11 | |
5-(Morpholinomethyl)-3-[(5-nitrofurfurylidene)-amino]-2-oxazolidinone | cancer | SQE | 139-91-3 | 01/abr/88 | 0,18 |
Mustard Gas | cancer | LC | 505-60-2 | 27/fev/87 | |
MX (3-chloro-4-dichloromethyl-5-hydroxy-2(5H)-furanone) | cancer | SQE | 77439-76-0 | 22/dez/00 | 0,11 |
Myclobutanil | developmental, male | AB | 88671-89-0 | 16/abr/99 | |
Nabam | developmental | AB | 142-59-6 | 30/mar/99 | |
Nafarelin acetate | developmental | FR | 86220-42-0 | 01/abr/90 | |
Nafenopin | cancer | SQE | 3771-19-5 | 01/abr/88 | |
Nalidixic acid | cancer | AB | 389-08-2 | 15/mai/98 | 28 |
Naphthalene | cancer | AB | 91-20-3 | 19/abr/02 | 5,8 |
1-Naphthylamine | cancer | LC | 134-32-7 | 01/out/89 | |
2-Naphthylamine | cancer | LC | 91-59-8 | 27/fev/87 | 0,4 |
Neomycin sulfate (internal use) | developmental | FR | 1405-10-3 | 01/out/92 | |
Netilmicin sulfate | developmental | FR | 56391-57-2 | 01/jul/90 | |
Nickel (Metallic) | cancer | LC | 7440-02-0 | 01/out/89 | |
Nickel acetate | cancer | LC | 373-02-4 | 01/out/89 | |
Nickel carbonate | cancer | LC | 3333-67-3 | 01/out/89 | |
Nickel carbonyl | cancer | SQE | 13463-39-3 | 01/out/87 | |
Nickel carbonyl | developmental | AB | 13463-39-3 | 01/set/96 | |
Nickel compounds | cancer | LC | --- | 07/mai/04 | |
Nickel hydroxide | cancer | LC | 12054-48-7; 12125-56-3 | 01/out/89 | |
Nickelocene | cancer | LC | 1271-28-9 | 01/out/89 | |
Nickel oxide | cancer | LC | 1313-99-1 | 01/out/89 | |
Nickel refinery dust from the pyrometallurgical process | cancer | SQE | --- | 01/out/87 | 0,8 |
Nickel subsulfide | cancer | SQE | 12035-72-2 | 01/out/87 | 0,4 |
Nicotine | developmental | FR | 54-11-5 | 01/abr/90 | |
Nifedipine | developmental, female, male | FR | 21829-25-4 | 29/jan/99 | |
Nimodipine | developmental | FR | 66085-59-4 | 24/abr/01 | |
Niridazole | cancer | SQE | 61-57-4 | 01/abr/88 | |
Nitrapyrin | cancer | AB | 1929-82-4 | 05/out/05 | |
Nitrapyrin | developmental | AB | 1929-82-4 | 30/mar/99 | |
Nitrilotriacetic acid | cancer | SQE | 139-13-9 | 01/jan/88 | 100 |
Nitrilotriacetic acid, trisodium salt monohydrate | cancer | SQE | 18662-53-8 | 01/abr/89 | 70 |
5-Nitroacenaphthene | cancer | SQE | 602-87-9 | 01/abr/88 | 6 |
5-Nitro-o-anisidine Delisted December 8, 2006 [Click here for the basis for delisting] | |||||
o-Nitroanisole | cancer | AB | 91-23-6 | 01/out/92 | |
Nitrobenzene | cancer | AB | 98-95-3 | 26/ago/97 | |
Nitrobenzene | male | AB | 98-95-3 | 30/mar/10 | |
4-Nitrobiphenyl | cancer | SQE | 92-93-3 | 01/abr/88 | |
6-Nitrochrysene | cancer | AB | 7496-02-8 | 01/out/90 | |
Nitrofen (technical grade) | cancer | SQE | 1836-75-5 | 01/jan/88 | 9 |
2-Nitrofluorene | cancer | AB | 607-57-8 | 01/out/90 | |
Nitrofurantoin | male | AB | 67-20-9 | 01/abr/91 | |
Nitrofurazone | cancer | AB | 59-87-0 | 01/jan/90 | 0,5 |
1-[(5-Nitrofurfurylidene)-amino]-2-imidazolidinone | cancer | SQE | 555-84-0 | 01/abr/88 | 0,4 |
N-[4-(5-Nitro-2-furyl)-2-thiazolyl]acetamide | cancer | SQE | 531-82-8 | 01/abr/88 | 0,5 |
Nitrogen mustard (Mechlorethamine) | cancer | SQE | 51-75-2 | 01/jan/88 | |
Nitrogen mustard (Mechlorethamine) | developmental | SQE | 51-75-2 | 01/jan/89 | |
Nitrogen mustard hydrochloride (Mechlorethamine hydrochloride) | cancer | SQE | 55-86-7 | 01/abr/88 | |
Nitrogen mustard hydrochloride (Mechlorethamine hydrochloride) | developmental | FR | 55-86-7 | 01/jul/90 | |
Nitrogen mustard N-oxide | cancer | SQE | 126-85-2 | 01/abr/88 | |
Nitrogen mustard N-oxide hydrochloride | cancer | SQE | 302-70-5 | 01/abr/88 | |
Nitromethane | cancer | AB | 75-52-5 | 01/mai/97 | 39 |
2-Nitropropane | cancer | SQE | 79-46-9 | 01/jan/88 | |
1-Nitropyrene | cancer | AB | 5522-43-0 | 01/out/90 | |
4-Nitropyrene | cancer | AB | 57835-92-4 | 01/out/90 | |
N-Nitrosodiethanolamine | cancer | SQE | 1116-54-7 | 01/jan/88 | 0,3 |
N-Nitrosodiethylamine | cancer | SQE | 55-18-5 | 01/out/87 | 0,02 |
N-Nitrosodimethylamine | cancer | SQE | 62-75-9 | 01/out/87 | 0,04 |
N-Nitrosodi-n-butylamine | cancer | SQE | 924-16-3 | 01/out/87 | 0,06 |
N-Nitrosodi-n-propylamine | cancer | SQE | 621-64-7 | 01/jan/88 | 0,1 |
p-Nitrosodiphenylamine | cancer | SQE | 156-10-5 | 01/jan/88 | 30 |
N-Nitrosodiphenylamine | cancer | SQE | 86-30-6 | 01/abr/88 | 80 |
3-(N-Nitrosomethylamino) propionitrile | cancer | AB | 60153-49-3 | 01/abr/90 | |
4-(N-Nitrosomethylamino)-1-(3-pyridyl)1-butanone | cancer | AB | 64091-91-4 | 01/abr/90 | 0,014 |
N-Nitrosomethylethylamine | cancer | LC | 10595-95-6 | 01/out/89 | 0,03 |
N-Nitrosomethylvinylamine | cancer | SQE | 4549-40-0 | 01/jan/88 | |
N-Nitrosomorpholine | cancer | SQE | 59-89-2 | 01/jan/88 | 0,1 |
N-Nitroso-N-ethylurea | cancer | SQE | 759-73-9 | 01/out/87 | 0,03 |
N-Nitroso-N-methylurea | cancer | SQE | 684-93-5 | 01/out/87 | 0,006 |
N-Nitroso-N-methylurethane | cancer | SQE | 615-53-2 | 01/abr/88 | 0,006 |
N-Nitrosonornicotine | cancer | SQE | 16543-55-8 | 01/jan/88 | 0,5 |
N-Nitrosopiperidine | cancer | SQE | 100-75-4 | 01/jan/88 | 0,07 |
N-Nitrosopyrrolidine | cancer | SQE | 930-55-2 | 01/out/87 | 0,3 |
N-Nitrososarcosine | cancer | SQE | 13256-22-9 | 01/jan/88 | |
o-Nitrotoluene | cancer | AB | 88-72-2 | 15/mai/98 | |
Nitrous oxide | developmental | LC | 10024-97-2 | 01/ago/08 | |
Norethisterone (Norethindrone) | cancer | LC | 68-22-4 | 01/out/89 | |
Norethisterone (Norethindrone) | developmental | FR | 68-22-4 | 01/abr/90 | |
Norethisterone acetate (Norethindrone acetate) | developmental | FR | 51-98-9 | 01/out/91 | |
Norethisterone (Norethindrone) /Ethinyl estradiol | developmental | FR | 68-22-4 57-63-6 | 01/abr/90 | |
Norethisterone (Norethindrone) /Mestranol | developmental | FR | 68-22-4 72-33-3 | 01/abr/90 | |
Norethynodrel | cancer | AB | 68-23-5 | 27/fev/01 | |
Norgestrel | developmental | FR | 6533-00-2 | 01/abr/90 | |
Ochratoxin A | cancer | AB | 303-47-9 | 01/jul/90 | |
Oil Orange SS | cancer | SQE | 2646-17-5 | 01/abr/88 | |
Oral contraceptives, combined | cancer | LC | --- | 01/out/89 | |
Oral contraceptives, sequential | cancer | LC | --- | 01/out/89 | |
Oryzalin | cancer | AB | 19044-88-3 | 12/set/08 | |
Oxadiazon | cancer | SQE | 19666-30-9 | 01/jul/91 | |
Oxadiazon | developmental | AB | 19666-30-9 | 15/mai/98 | |
Oxazepam | cancer | AB | 604-75-1 | 01/out/94 | |
Oxazepam | developmental | FR | 604-75-1 | 01/out/92 | |
p,p'-Oxybis(benzenesulfonyl hydrazide) | developmental | LC | 80-51-3 | 07/ago/09 | |
Oxydemeton methyl | female, male | AB | 301-12-2 | 06/nov/98 | |
Oxymetholone | cancer | SQE | 434-07-1 | 01/jan/88 | |
Oxymetholone | developmental | FR | 434-07-1 | 01/mai/97 | |
Oxytetracycline (internal use) | developmental | FR | 79-57-2 | 01/jan/91 | |
Oxytetracycline hydrochloride (internal use) | developmental | FR | 2058-46-0 | 01/out/91 | |
Oxythioquinox (Chinomethionat) | cancer | AB | 2439-01-2 | 20/ago/99 | |
Oxythioquinox (Chinomethionat) | developmental | AB | 2439-01-2 | 06/nov/98 | |
Paclitaxel | developmental, female, male | FR | 33069-62-4 | 26/ago/97 | |
Palygorskite fibers (> 5mm in length) | cancer | AB | 12174-11-7 | 28/dez/99 | |
Panfuran S | cancer | SQE | 794-93-4 | 01/jan/88 | |
Paramethadione | developmental | FR | 115-67-3 | 01/jul/90 | |
Penicillamine | developmental | FR | 52-67-5 | 01/jan/91 | |
Pentachlorophenol | cancer | AB | 87-86-5 | 01/jan/90 | 40 |
Pentobarbital sodium | developmental | FR | 57-33-0 | 01/jul/90 | |
Pentostatin | developmental | FR | 53910-25-1 | 01/set/96 | |
Phenacemide | developmental | FR | 63-98-9 | 01/jul/90 | |
Phenacetin | cancer | LC | 62-44-2 | 01/out/89 | 300 |
Phenazopyridine | cancer | SQE | 94-78-0 | 01/jan/88 | 4 |
Phenazopyridine hydrochloride | cancer | SQE | 136-40-3 | 01/jan/88 | 5 |
Phenesterin | cancer | SQE | 3546-10-9 | 01/jul/89 | 0,005 |
Phenobarbital | cancer | AB | 50-06-6 | 01/jan/90 | 2 |
Phenolphthalein | cancer | AB | 77-09-8 | 15/mai/98 | |
Phenoxybenzamine | cancer | SQE | 59-96-1 | 01/abr/88 | 0,2 |
Phenoxybenzamine hydrochloride | cancer | SQE | 63-92-3 | 01/abr/88 | 0,3 |
Phenprocoumon | developmental | FR | 435-97-2 | 01/out/92 | |
o-Phenylenediamine and its salts | cancer | AB | 95-54-5 | 15/mai/98 | |
o-Phenylenediamine | 26 | ||||
o-Phenylenediamine dihydochloride | 44 | ||||
Phenyl glycidyl ether | cancer | AB | 122-60-1 | 01/out/90 | 5 |
Phenyl glycidyl ether | male | LC | 122-60-1 | 07/ago/09 | |
Phenylhydrazine and its salts | cancer | AB | --- | 01/jul/92 | |
Phenylhydrazine | 1 | ||||
Phenylhydrazine hydrochloride | 1,4 | ||||
o-Phenylphenate, sodium | cancer | AB | 132-27-4 | 01/jan/90 | 200 |
o-Phenylphenol | cancer | AB | 90-43-7 | 04/ago/00 | |
Phenylphosphine | developmental | LC | 638-21-1 | 07/ago/09 | |
PhiP(2-Amino-1-methyl-6-phenylimidazol[4,5-b]pyridine) | cancer | AB | 105650-23-5 | 01/out/94 | |
Pimozide | developmental, female | FR | 2062-78-4 | 20/ago/99 | |
Pipobroman | developmental | FR | 54-91-1 | 01/jul/90 | |
Pirimicarb | cancer | AB | 23103-98-2 | 01/jul/08 | |
Plicamycin | developmental | FR | 18378-89-7 | 01/abr/90 | |
Polybrominated biphenyls | cancer | SQE | --- | 01/jan/88 | 0,02 |
Polybrominated biphenyls | developmental | AB | --- | 01/out/94 | |
Polychlorinated biphenyls | cancer | LC | --- | 01/out/89 | 0,09 |
Polychlorinated biphenyls | developmental | SQE | --- | 01/jan/91 | |
Polychlorinated biphenyls (containing 60 or more percent percent chlorine by molecular weight) | cancer | SQE | --- | 01/jan/88 | |
Polychlorinated dibenzo-p-dioxins | cancer | FR | --- | 01/out/92 | |
Polychlorinated dibenzofurans | cancer | FR | --- | 01/out/92 | |
Polygeenan | cancer | SQE | 53973-98-1 | 01/jan/88 | 1200 |
Ponceau MX | cancer | SQE | 3761-53-3 | 01/abr/88 | 200 |
Ponceau 3R | cancer | SQE | 3564-09-8 | 01/abr/88 | 40 |
Potassium bromate | cancer | AB | 7758-01-2 | 01/jan/90 | 1 |
Potassium dimethyldithiocarbamate | developmental | AB | 128-03-0 | 30/mar/99 | 720 |
Pravastatin sodium | developmental | FR | 81131-70-6 | 03/mar/00 | |
Prednisolone sodium phosphate | developmental | FR | 125-02-0 | 20/ago/99 | |
Primidone | cancer | AB | 125-33-7 | 20/ago/99 | |
Procarbazine | cancer | SQE | 671-16-9 | 01/jan/88 | 0,05 |
Procarbazine hydrochloride | cancer | SQE | 366-70-1 | 01/jan/88 | 0,06 |
Procarbazine hydrochloride | developmental | FR | 366-70-1 | 01/jul/90 | |
Procymidone | cancer | AB | 32809-16-8 | 01/out/94 | |
Progesterone | cancer | SQE | 57-83-0 | 01/jan/88 | |
Pronamide | cancer | AB | 23950-58-5 | 01/mai/96 | |
Propachlor | cancer | AB | 1918-16-7 | 27/fev/01 | |
1,3-Propane sultone | cancer | SQE | 1120-71-4 | 01/jan/88 | 0,3 |
Propargite | cancer | AB | 2312-35-8 | 01/out/94 | |
Propargite | developmental | AB | 2312-35-8 | 15/jun/99 | |
beta-Propiolactone | cancer | SQE | 57-57-8 | 01/jan/88 | 0,05 |
Propoxur | cancer | AB | 114-26-1 | 11/ago/06 | |
Propylene glycol mono-t-butyl ether | cancer | AB | 57018-52-7 | 11/jun/04 | |
Propylene oxide | cancer | SQE | 75-56-9 | 01/out/88 | |
Propylthiouracil | cancer | SQE | 51-52-5 | 01/jan/88 | 0,7 |
Propylthiouracil | developmental | FR | 51-52-5 | 01/jul/90 | |
Pymetrozine | cancer | AB | 123312-89-0 | 22/mar/11 | |
Pyridine | cancer | AB | 110-86-1 | 17/mai/02 | |
Pyrimethamine | developmental | FR | 58-14-0 | 29/jan/99 | |
Quazepam | developmental | FR | 36735-22-5 | 26/ago/97 | |
Quinoline and its strong acid salts | cancer | SQE | --- | 24/out/97 | |
Quizalofop-ethyl | male | SQE | 76578-14-8 | 24/dez/99 | 590 |
Radionuclides | cancer | SQE | --- | 01/jul/89 | |
Reserpine | cancer | LC | 50-55-5 | 01/out/89 | 0,06 |
Residual (heavy) fuel oils | cancer | AB | --- | 01/out/90 | |
Resmethrin | cancer | AB | 10453-86-8 | 01/jul/08 | |
Resmethrin | developmental | AB | 10453-86-8 | 06/nov/98 | |
Retinol/retinyl esters, when in daily dosages in excess of 10,000 IU, or 3,000 retinol equivalents. (NOTE: Retinol/retinyl esters are required and essential for maintenance of normal reproductive function. The recommended daily level during pregnancy is 8,000 IU.) | developmental | SQE | --- | 01/jul/89 | |
Ribavirin | developmental | FR | 36791-04-5 | 01/abr/90 | |
Ribavirin | male | FR | 36791-04-5 | 27/fev/01 | |
Riddelliine | cancer | LC | 23246-96-0 | 03/dez/04 | |
Rifampin | developmental, female | FR | 13292-46-1 | 27/fev/01 | |
Saccharin Delisted April 6, 2001 [Click here for the basis for delisting] | |||||
Saccharin, sodium Delisted January 17, 2003 [Click here for the basis for delisting] | |||||
Safrole | cancer | SQE | 94-59-7 | 01/jan/88 | 3 |
Salted fish, Chinese-style | cancer | LC | --- | 29/abr/11 | |
Secobarbital sodium | developmental | FR | 309-43-3 | 01/out/92 | |
Selenium sulfide | cancer | LC | 7446-34-6 | 01/out/89 | |
Sermorelin acetate | developmental | FR | --- | 20/ago/99 | |
Shale-oils | cancer | AB | 68308-34-9 | 01/abr/90 | |
Silica, crystalline (airborne particles of respirable size) | cancer | SQE | --- | 01/out/88 | |
Sodium dimethyldithiocarbamate | developmental | AB | 128-04-1 | 30/mar/99 | 23 (oral) 58 (oral) as a 40% pesticidal formulation |
Sodium fluoroacetate | male | AB | 62-74-8 | 06/nov/98 | |
Soots, tars, and mineral oils (untreated and mildly treated oils and used engine oils) | cancer | LC | --- | 27/fev/87 | |
Spirodiclofen | cancer | AB | 148477-71-8 | 08/out/10 | |
Spironolactone | cancer | FR | 52-01-7 | 01/mai/97 | |
Stanozolol | cancer | FR | 10418-03-8 | 01/mai/97 | |
Sterigmatocystin | cancer | SQE | 10048-13-2 | 01/abr/88 | 0,02 |
Streptomycin sulfate | developmental | 3810-74-0 | 01/jan/91 | ||
Streptozocin (streptozotocin) | developmental, female, male | FR | 18883-66-4 | 20/ago/99 | |
Streptozotocin (streptozocin) | cancer | SQE | 18883-66-4 | 01/jan/88 | 0,006 |
Strong inorganic acid mists containing sulfuric acid | cancer | AB | --- | 14/mar/03 | |
Styrene oxide | cancer | SQE | 96-09-3 | 01/out/88 | 4 |
Sulfallate | cancer | SQE | 95-06-7 | 01/jan/88 | 4 |
Sulfasalazine (salicylazosulfapyridine) | cancer | AB | 599-79-1 | 15/mai/98 | |
Sulfasalazine (salicylazosulfapyridine) | male | FR | 599-79-1 | 29/jan/99 | |
Sulfur dioxide | developmental | SQE | 7446-09-5 | 29/jul/11 | |
Sulindac | developmental, female | FR | 38194-50-2 | 29/jan/99 | |
Talc containing asbestiform fibers | cancer | AB | --- | 01/abr/90 | |
Tamoxifen and its salts | cancer | SQE | 10540-29-1 | 01/set/96 | |
Tamoxifen citrate | developmental | FR | 54965-24-1 | 01/jul/90 | |
Temazepam | developmental | FR | 846-50-4 | 01/abr/90 | |
Teniposide | developmental | FR | 29767-20-2 | 01/set/96 | |
Terbacil | developmental | AB | 5902-51-2 | 18/mai/99 | |
Terrazole | cancer | AB | 2593-15-9 | 01/out/94 | |
Testosterone and its esters | cancer | SQE | 58-22-0 | 01/abr/88 | |
Testosterone cypionate | developmental | FR | 58-20-8 | 01/out/91 | |
Testosterone enanthate | developmental | FR | 315-37-7 | 01/abr/90 | |
3,3',4,4'-Tetrachloroazobenzene | cancer | AB | 14047-09-7 | 24/jul/12 | |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) | cancer | SQE | 1746-01-6 | 01/jan/88 | 0,000005 |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) | developmental | AB | 1746-01-6 | 01/abr/91 | |
1,1,2,2-Tetrachloroethane | cancer | AB | 79-34-5 | 01/jul/90 | 3 |
Tetrachloroethylene (Perchloroethylene) | cancer | SQE | 127-18-4 | 01/abr/88 | 14 |
p-a,a,a-Tetrachlorotoluene | cancer | AB | 5216-25-1 | 01/jan/90 | |
Tetracycline (internal use) | developmental | FR | 60-54-8 | 01/out/91 | |
Tetracyclines (internal use) | developmental | FR | --- | 01/out/92 | |
Tetracycline hydrochloride (internal use) | developmental | FR | 64-75-5 | 01/jan/91 | |
Tetrafluoroethylene | cancer | AB | 116-14-3 | 01/mai/97 | |
Tetranitromethane | cancer | AB | 509-14-8 | 01/jul/90 | 0,059 |
Thalidomide | developmental | SQE | 50-35-1 | 01/jul/87 | |
Thioacetamide | cancer | SQE | 62-55-5 | 01/jan/88 | 0,1 |
4,4'-Thiodianiline | cancer | SQE | 139-65-1 | 01/abr/88 | 0,05 |
Thiodicarb | cancer | AB | 59669-26-0 | 20/ago/99 | |
Thioguanine | developmental | FR | 154-42-7 | 01/jul/90 | |
Thiophanate methyl | female, male | AB | 23564-05-8 | 18/mai/99 | 600 (oral) |
Thiouracil | cancer | AB | 141-90-2 | 11/jun/04 | |
Thiourea | cancer | SQE | 62-56-6 | 01/jan/88 | 10 |
Thorium dioxide | cancer | LC | 1314-20-1 | 27/fev/87 | |
Titanium dioxide (airborne, unbound particles of respirable size) | cancer | LC | --- | 02/set/11 | |
Tobacco, oral use of smokeless products | cancer | SQE | --- | 01/abr/88 | |
Tobacco smoke | cancer | SQE | --- | 01/abr/88 | |
Tobacco smoke (primary) | developmental, female, male | SQE | --- | 01/abr/88 | |
Tobramycin sulfate | developmental | FR | 49842-07-1 | 01/jul/90 | |
Toluene | developmental | SQE | 108-88-3 | 01/jan/91 | 7000c |
Toluene | female | LC | 108-88-3 | 07/ago/09 | |
Toluene diisocyanate | cancer | LC | 26471-62-5 | 01/out/89 | 20 |
o-Toluidine | cancer | SQE | 95-53-4 | 01/jan/88 | 4 |
o-Toluidine hydrochloride | cancer | SQE | 636-21-5 | 01/jan/88 | 5 |
para-Toluidine Delisted October 29, 1999 [Click here for the basis for delisting] | |||||
Toxaphene (Polychlorinated camphenes) | cancer | SQE | 8001-35-2 | 01/jan/88 | 0,6 |
Toxins derived from Fusarium moniliforme (Fusarium verticillioides) | cancer | LC | --- | 07/ago/09 | |
Treosulfan | cancer | LC | 299-75-2 | 27/fev/87 | |
Triadimefon | developmental, female, male | AB | 43121-43-3 | 30/mar/99 | |
Triazolam | developmental | FR | 28911-01-5 | 01/abr/90 | |
S,S,S-Tributyl phosphorotrithioate (Tribufos, DEF) | cancer | AB | 78-48-8 | 25/fev/11 | |
Tributyltin methacrylate | developmental | AB | 2155-70-6 | 01/dez/99 | |
Trichlormethine (Trimustine hydrochloride) | cancer | AB | 817-09-4 | 01/jan/92 | |
Trichloroethylene | cancer | SQE | 79-01-6 | 01/abr/88 | 14 (oral) 50 (inhalation) |
2,4,6-Trichlorophenol | cancer | SQE | 88-06-2 | 01/jan/88 | 10 |
1,2,3-Trichloropropane | cancer | AB | 96-18-4 | 01/out/92 | |
Trientine hydrochloride | developmental | FR | 38260-01-4 | 27/fev/01 | |
Triforine | developmental | AB | 26644-46-2 | 18/jun/99 | |
1,3,5-Triglycidyl-s-triazinetrione | male | LC | 2451-62-9 | 07/ago/09 | |
Trilostane | developmental | FR | 13647-35-3 | 01/abr/90 | |
Trimethadione | developmental | FR | 127-48-0 | 01/jan/91 | |
2,4,5-Trimethylaniline and its strong acid salts | cancer | SQE | --- | 24/out/97 | |
Trimethyl phosphate | cancer | AB | 512-56-1 | 01/mai/96 | 24 |
Trimetrexate glucuronate | developmental | FR | 82952-64-5 | 26/ago/97 | |
2,4.6-Trinitrotoluene (TNT) | cancer | SQE | 118-96-7 | 19/dez/08 | 8,2 |
Triphenyltin hydroxide | cancer | AB | 76-87-9 | 01/jul/92 | |
Triphenyltin hydroxide | developmental | AB | 76-87-9 | 18/mar/02 | |
Tris(aziridinyl)-p-benzoquinone (Triaziquone) Delisted December 8, 2006 [Click here for the basis for delisting] | |||||
Tris(1-aziridinyl)phosphine sulfide (Thiotepa) | cancer | SQE | 52-24-4 | 01/jan/88 | 0,06 |
Tris(2-chloroethyl) phosphate | cancer | AB | 115-96-8 | 01/abr/92 | |
Tris(2,3-dibromopropyl)phosphate | cancer | SQE | 126-72-7 | 01/jan/88 | 0,3 |
Tris(1,3-dichloro-2-propyl) phosphate (TDCPP) | cancer | SQE | 13674-87-8 | 28/out/11 | 5,4 |
Trp-P-1 (Tryptophan-P-1) | cancer | SQE | 62450-06-0 | 01/abr/88 | 0,03 |
Trp-P-2 (Tryptophan-P-2) | cancer | SQE | 62450-07-1 | 01/abr/88 | 0,2 |
Trypan blue (commercial grade) | cancer | LC | 72-57-1 | 01/out/89 | |
Unleaded gasoline (wholly vaporized) | cancer | SQE | --- | 01/abr/88 | |
Uracil mustard | cancer | SQE | 66-75-1 | 01/abr/88 | |
Uracil mustard | developmental, female, male | FR | 66-75-1 | 01/jan/92 | |
Urethane (Ethyl carbamate) | cancer | SQE | 51-79-6 | 01/jan/88 | 0,7 |
Urethane (Ethyl carbamate) | developmental | AB | 51-79-6 | 01/out/94 | |
Urofollitropin | developmental | FR | 97048-13-0 | 01/abr/90 | |
Valproate (Valproic acid) | developmental | SQE | 99-66-1 | 01/jul/87 | |
Vanadium pentoxide (orthorhombic crystalline form) | cancer | AB | 1314-62-1 | 11/fev/05 | |
Vinblastine sulfate | developmental | FR | 143-67-9 | 01/jul/90 | |
Vinclozolin | cancer | AB | 50471-44-8 | 20/ago/99 | |
Vinclozolin | developmental | AB | 50471-44-8 | 15/mai/98 | |
Vincristine sulfate | developmental | FR | 2068-78-2 | 01/jul/90 | |
Vinyl bromide | cancer | SQE | 593-60-2 | 01/out/88 | |
Vinyl chloride | cancer | LC | 75-01-4 | 27/fev/87 | 3 |
4-Vinylcyclohexene | cancer | AB | 100-40-3 | 01/mai/96 | |
4-Vinylcyclohexene | female, male | LC | 100-40--3 | 07/ago/09 | |
4-Vinyl-1-cyclohexene diepoxide (Vinyl cyclohexenedioxide) | cancer | AB | 106-87-6 | 01/jul/90 | |
Vinyl cyclohexene dioxide (4-Vinyl-1-cyclohexene diepoxide) | female, male | LC | 106-87-6 | 01/ago/08 | |
Vinyl fluoride | cancer | AB | 75-02-5 | 01/mai/97 | |
Vinyl trichloride (1,1,2-Trichloroethane) | cancer | AB | 79-00-5 | 01/out/90 | 10 |
Warfarin | developmental | SQE | 81-81-2 | 01/jul/87 | |
Wood dust | cancer | LC | --- | 18/dez/09 | |
2,6-Xylidine (2,6-Dimethylaniline) | cancer | AB | 87-62-7 | 01/jan/91 | 110 |
Zalcitabine | cancer | LC | 7481-89-2 | 07/ago/09 | |
Zidovudine (AZT) | cancer | LC | 30516-87-1 | 18/dez/09 | |
Zileuton | cancer, developmental, female | FR | 111406-87-2 | 22/dez/00 | |
Zineb Delisted October 29, 1999 [Click here for the basis for delisting] | |||||
a Where a source or product results in exposures by multiple routes, the total exposure must be considered. For example, the MADL for benzene is exceeded when the absorbed dose exceeds 24 µg/day. If only inhalation and oral exposure occurs, the benzene MADL is exceeded when: (oral dose ÷ 24 µg/day) + (inhalation dose ÷ 49 µg/day) > 1.0. | |||||
b Levels for male children and adolescents were calculated by application of the default bodyweights specified in Section 25703(a)(8) to the procedure specified in Sections 25801 and 25803 | |||||
c Level represents absorbed dose (rounded from 6,525 µg/day ). Since 100% of ingested toluene is absorbed, oral dose is equivalent to administered dose. It is assumed that roughly 50% of the dose administered by the inhalation route is absorbed. Therefore the MADL for inhaled toluene is 13,000 µg/day (rounded from 13,050 µg/day ), corresponding to an absorbed dose of 6,525 µg/day. | |||||
quarta-feira, 1 de maio de 2013
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